From the github page:
The design goal of ProgPoW is to have the algorithm’s requirements match what is available on commodity GPUs: If the algorithm were to be implemented on a custom ASIC there should be little opportunity for efficiency gains compared to a commodity GPU.
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While the goal of “ASIC resistance” is valuable, the entire concept of “ASIC resistance” is a bit of a fallacy. CPUs and GPUs are themselves ASICs. Any algorithm that can run on a commodity ASIC (a CPU or GPU) by definition can have a customized ASIC created for it with slightly less functionality. Some algorithms are intentionally made to be “ASIC friendly” - where an ASIC implementation is drastically more efficient than the same algorithm running on general purpose hardware. The protection that this offers when the coin is unknown also makes it an attractive target for a dedicate mining ASIC company as soon as it becomes useful.
Therefore, ASIC resistance is: the efficiency difference of specilized hardware versus hardware that has a wider adoption and applicability. A smaller efficiency difference between custom vs general hardware mean higher resistance and a better algorithm. This efficiency difference is the proper metric to use when comparing the quality of PoW algorithms. Efficiency could mean absolute performance, performance per watt, or performance per dollar - they are all highly correlated. If a single entity creates and controls an ASIC that is drastically more efficient, they can gain 51% of the network hashrate and possibly stage an attack.